Alunbrig prescribing information

As a healthcare provider, it is essential to understand the prescribing information of any medication before administering it to patients. Alunbrig (brigatinib) is a medication used for the treatment of metastatic non-small cell lung cancer (NSCLC) that has progressed despite treatment with other therapies. Alunbrig price, Alunbrig price, Alunbrig sales, Alunbrig pi, lunbrig copay card

In this article, I will provide a thorough breakdown of Alunbrig prescribing information, including its key components, dosage and administration, safety information, possible side effects and warnings, price and insurance coverage, sales and market trends, and utilizing Alunbrig copay card for cost savings.

Introduction to Alunbrig Prescribing Information

Alunbrig is an oral medication that comes in the form of tablets, and it is a tyrosine kinase inhibitor that targets ALK and ROS1 gene mutations. Alunbrig is indicated for the treatment of adult patients with metastatic NSCLC that has progressed despite treatment with crizotinib or who have experienced intolerable side effects from crizotinib. Alunbrig is not recommended for patients with severe liver impairment or those taking strong CYP3A inhibitors. Alunbrig price

Understanding the Importance of Alunbrig Prescribing Information

The prescribing information of Alunbrig provides guidance for healthcare providers on how to administer the medication safely and effectively. Alunbrig price It contains information on the drug’s indications, dosage, administration, contraindications, warnings, precautions, and possible side effects. Understanding this information is crucial to ensure that the patient receives the appropriate treatment, Alunbrig pi  and the medication’s safety and efficacy are maximized.

Key Components of Alunbrig Prescribing Information

The prescribing information of Alunbrig contains several key components that healthcare providers need to be familiar with. Alunbrig sales These include indications and usage, dosage and administration, contraindications, warnings and precautions, adverse reactions, drug interactions, use in specific populations, and patient counseling information. Let’s take a closer look at each of these components.

Indications and Usage

Alunbrig is indicated for the treatment of adult patients with metastatic NSCLC that has progressed despite treatment with crizotinib or who have experienced intolerable side effects from crizotinib. The recommended dosage of Alunbrig is 90 mg orally once daily for the first seven days, followed by 180 mg orally once daily thereafter. lunbrig copay card

Dosage and Administration

Alunbrig should be taken on an empty stomach, at least one hour before or two hours after eating. The tablets should be swallowed whole and not crushed, chewed, or broken. If a dose is missed, the patient should take the missed dose as soon as possible, unless it is less than 12 hours until the next dose, in which case, the patient should skip the missed dose. Alunbrig price

Contraindications

Alunbrig is contraindicated in patients with severe hypersensitivity to brigatinib or any of its components. It is also contraindicated in patients with severe liver impairment or those taking strong CYP3A inhibitors. Alunbrig pi

Warnings and Precautions

Alunbrig may cause interstitial lung disease (ILD) or pneumonitis, which can be fatal. Patients should be monitored for new or worsening respiratory symptoms, such as dyspnea, cough, or fever, and treatment should be withheld or discontinued if ILD or pneumonitis is suspected.

Adverse Reactions

The most common adverse reactions of Alunbrig include nausea, diarrhea, fatigue, cough, headache, and hypertension. Other adverse reactions may include rash, myalgia, anemia, and increased amylase. lunbrig copay card

Drug Interactions

Alunbrig may interact with other medications, such as strong CYP3A inhibitors and inducers, and drugs that prolong the QT interval. Alunbrig price Healthcare providers should review the patient’s medication history before prescribing Alunbrig to avoid potential drug interactions. Alunbrig price

Use in Specific Populations

Alunbrig is not recommended for use in pregnant women. And women of reproductive potential should use effective contraception during treatment and for at least four months after the last dose. It is not known if Alunbrig is excreted in human milk. Alunbrig pi And breastfeeding should be avoided during treatment and for at least one week after the last dose.

Patient Counseling Information

Patients should be advised to take Alunbrig exactly as prescribed and to contact their healthcare provider if they experience new or worsening respiratory symptoms, such as dyspnea, cough, or fever. Patients should also be advised to avoid grapefruit and grapefruit juice during treatment with Alunbrig.

Interpreting the Dosage and Administration Section of Alunbrig Prescribing Information

The dosage and administration section of Alunbrig prescribing information provides guidance on how to administer the medication to patients.  Alunbrig price The recommended dosage of Alunbrig is 90 mg orally once daily for the first seven days, followed by 180 mg orally once daily thereafter. Alunbrig price

Alunbrig should be taken on an empty stomach, at least one hour before or two hours after eating. The tablets should be swallowed whole and not crush, chew, or broke. Alunbrig pi  If a dose is miss, the patient should take the miss dose as soon as possible. Unless it is less than 12 hours until the next dose, in which case, the patient should skip the missed dose.

Safety Information in Alunbrig Prescribing Information

The safety information of Alunbrig prescribing information includes warnings and precautions, contraindications. And adverse reactions. Alunbrig may cause interstitial lung disease (ILD) or pneumonitis, which can be fatal. Patients should be monitored for new or worsening respiratory symptoms, such as dyspnea, cough, or fever, and treatment should be withheld or discontinued if ILD or pneumonitis is suspected. lunbrig copay card

Alunbrig is contraindicated in patients with severe hypersensitivity to brigatinib or any of its components. It is also contraindicated in patients with severe liver impairment or those taking strong CYP3A inhibitors. The most common adverse reactions of Alunbrig include nausea, diarrhea, fatigue, cough, headache, and hypertension. Other adverse reactions may include rash, myalgia, anemia, and increased amylase.

Possible Side Effects and Warnings in Alunbrig Prescribing Information

The possible side effects and warnings of Alunbrig prescribing information include interstitial lung disease (ILD) or pneumonitis, hepatotoxicity, hypertension, and bradycardia. Patients should be monitor for new or worsening respiratory symptoms. Alunbrig price Such as dyspnea, cough, or fever, and treatment should be withheld or discontinued if ILD or pneumonitis is suspected. Alunbrig pi

Alunbrig may also cause hepatotoxicity, which can be severe and may lead to liver failure or death. Patients should be monitored for signs of hepatotoxicity, such as elevated liver function tests. And treatment should be withheld or discontinued if hepatotoxicity is suspected.

Alunbrig may cause hypertension, which can be severe and may lead to hypertensive crisis or hypertensive encephalopathy. Patients should be monitored for hypertension and treated if necessary.

Alunbrig may also cause bradycardia, which can be severe and may lead to syncope or cardiac arrest. Patients should be monitored for bradycardia and treated if necessary.

Alunbrig Price and Insurance Coverage

The cost of Alunbrig can vary depending on the patient’s insurance coverage, geographic location, and other factors. Alunbrig price The wholesale acquisition cost (WAC) of Alunbrig is approximately $17,000 for a 30-day supply of 90 mg tablets and $34,000 for a 30-day supply of 180 mg tablets.

Patients may be eligible for financial assistance through Alunbrig’s copay card program. This program provides eligible patients with a copay card that covers up to $26,000 in out-of-pocket expenses per year. Patients can apply for the copay card online or by calling 1-844-ALUNBRIG (258-6274).

Alunbrig Sales and Market Trends

Alunbrig is a relatively new medication that was approve by the FDA in 2017. According to a report by GlobalData, Alunbrig is expect to generate global sales of approximately $1.3 billion by 2026. The report also predicts that Alunbrig will become the third most prescribed drug in the ALK-inhibitor class. After Xalkori and Alecensa. lunbrig copay card

Utilizing Alunbrig Copay Card for Cost Savings

Patients who are prescribe Alunbrig may be eligible for financial assistance through Alunbrig’s copay card program. This program provides eligible patients with a copay card that covers up to $26,000 in out-of-pocket expenses per year. Patients can apply for the copay card online or by calling 1-844-ALUNBRIG (258-6274).

Conclusion: The Importance of Understanding Alunbrig Prescribing Information for Healthcare Providers and Patients

In conclusion, understanding the prescribing information of Alunbrig is essential for healthcare providers to ensure the safe and effective administration of the medication to patients. Alunbrig price The prescribing information contains crucial information on the drug’s indications, dosage, administration, contraindications, warnings, precautions, and possible side effects. Patients who are prescribe Alunbrig may be eligible for financial assistance through Alunbrig’s copay card program. Which can help reduce the cost of treatment.