Florkum 30

Florkum 30 is a broad-spectrum antimicrobial veterinary product primarily used to treat bacterial infections in livestock. Its active ingredient, Florfenicol, belongs to the amphenicol class of antibiotics and is effective against a wide range of Gram-positive and Gram-negative bacteria.

Active Ingredient
Florfenicol (30% concentration or 300 mg/mL in injectable formulations):
A synthetic derivative of chloramphenicol.
It works by inhibiting bacterial protein synthesis, exerting a bacteriostatic effect, and sometimes showing bactericidal activity at higher concentrations.
Indications
Florkum 30 is used to treat bacterial infections in various species, especially where florfenicol-sensitive bacteria are present.

Cattle:

Bovine Respiratory Disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
Foot Rot caused by Fusobacterium necrophorum and Bacteroides melaninogenicus.
Swine:
Swine Respiratory Disease (SRD) caused by Actinobacillus pleuropneumoniae and Pasteurella multocida.
Secondary infections from gastrointestinal pathogens.
Sheep and Goats:
Bacterial respiratory and gastrointestinal infections.
Poultry:
Respiratory infections caused by Escherichia coli and other bacterial pathogens.
Dosage and Administration
The dosage of Florkum 30 varies depending on the species, weight, and severity of infection. Always follow veterinary guidance.

Cattle:

Dose: 20 mg/kg body weight (1 mL per 15 kg).
Route: Intramuscular (IM) or Subcutaneous (SC).
Frequency: Administer once daily for 2 days. Alternatively, a single dose of 40 mg/kg (2 mL/15 kg) can be given for extended effect.
Swine:
Dose: 15 mg/kg body weight (1 mL per 20 kg).
Route: Intramuscular (IM).
Frequency: Administer once daily for 3 days.
Sheep and Goats:
Dose: 20 mg/kg body weight (1 mL per 15 kg).
Route: IM.
Frequency: Daily for 2–3 days.
Poultry:
Florfenicol may also be available in oral formulations for poultry, administered in drinking water. Dosage and frequency depend on the product and species. florkum 30
Pharmacokinetics
Absorption: Rapid absorption after injection.
Distribution: Well-distributed in tissues, particularly in the lungs, liver, and kidneys.
Elimination: Primarily through urine and bile.
Withdrawal Periods

Cattle:

Meat: 28–44 days (depending on dosage and administration route).
Milk: Not approved for use in lactating dairy cattle producing milk for human consumption.
Swine:

Meat: 14–21 days (depending on local regulations).
Sheep/Goats:

Meat: 28–30 days.
Milk: Use only under veterinary advice.
Poultry:

Meat: 7–10 days (for oral formulations).
Side Effects
Florkum 30 is generally well-tolerated, but potential side effects may include:

Injection Site Reactions:
Mild swelling, tenderness, or irritation at the injection site. florkum 30
Appetite Reduction:
Temporary loss of appetite or mild diarrhea in some animals.
Rare Reactions:
In rare cases, liver or kidney function may be mildly affected.
Contraindications

Lactating Animals:

Not recommended for animals producing milk for human consumption.
Allergic Reactions:
Avoid in animals with known hypersensitivity to florfenicol.
Severely Compromised Animals:
Use cautiously in animals with severe liver or kidney disease.
Precautions
Proper Injection Techniques:
Ensure proper site rotation to avoid localized reactions.
Species-Specific Use:
Only use in species for which the product is intended. florkum 30

Antimicrobial Stewardship:

Avoid overuse to prevent antimicrobial resistance.
Storage
Store at temperatures between 15°C–25°C (59°F–77°F).
Protect from light and freezing.
Shake well before use.
Packaging
Typically available as an injectable solution in vials of varying volumes (e.g., 100 mL, 250 mL).

Key Points

Broad-Spectrum Efficacy: Effective against a wide range of bacterial infections in livestock.
Reliable Safety Profile: Minimal side effects when used correctly.
Convenient Dosing: Long-lasting effects at high doses reduce the need for repeated administration.