Florfarma 30

Florfarma 30 for cattles is an antimicrobial drug widely used in veterinary medicine. Its primary active ingredient is Florfenicol, a broad-spectrum antibiotic belonging to the amphenicol class, effective against a variety of bacterial infections in livestock, particularly in respiratory and gastrointestinal diseases.

Active Ingredient
Florfenicol (30% concentration or 300 mg/mL in the injectable formulation).
Synthetic derivative of chloramphenicol.
Bacteriostatic, but exhibits bactericidal activity at higher concentrations by inhibiting bacterial protein synthesis.
Indications (Uses)
Florfarma 30 is primarily indicated for the treatment and prevention of bacterial infections caused by susceptible organisms, including:

Cattle:

Bovine Respiratory Disease (BRD) caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
Foot Rot caused by Fusobacterium necrophorum and Bacteroides melaninogenicus.
Swine:
Swine Respiratory Disease (SRD) caused by Actinobacillus pleuropneumoniae and Pasteurella multocida.
Gastrointestinal Infections, including those caused by bacterial enteritis.
Poultry:
Respiratory Infections caused by E. coli and other pathogens.
Sheep and Goats:
Respiratory and gastrointestinal bacterial infections.
Dosage and Administration
The dosage and administration depend on the species and the condition being treated. Florfarma 30 is typically administered via injection.

General Dosing Guidelines:
Cattle:

Dose: 20 mg/kg body weight (1 mL/15 kg body weight).
Route: Intramuscular (IM) or subcutaneous (SC).
Frequency: Administer once daily for 2 consecutive days. If necessary, a single SC dose of 40 mg/kg can be given for extended treatment duration.
Swine:

Dose: 15 mg/kg body weight (1 mL/20 kg body weight).
Route: Intramuscular (IM).
Frequency: Administer once daily for 3 days.
Sheep and Goats:

Dose: 20 mg/kg body weight (1 mL/15 kg body weight).
Route: IM.
Frequency: Daily for 2–3 days.
Poultry:

Oral administration may be used in some formulations (e.g., water-soluble powder).
Pharmacokinetics
Absorption: Rapidly absorbed after injection.
Distribution: Widely distributed in tissues, particularly in lungs, liver, and kidneys.
Elimination: Primarily excreted through urine and bile. Florfarma 30 for cattles
Withdrawal Periods

Cattle:

Meat: 28-44 days after last treatment (depending on dose and route).
Milk: Not approved for use in lactating cattle producing milk for human consumption.
Swine:

Meat: 14-21 days (depending on local regulations).
Sheep/Goats:

Meat: 28-30 days.
Milk: Use only under veterinary guidance.
Poultry:

Meat: 7-10 days (for oral formulations).
Always verify withdrawal periods with local regulatory authorities.

Side Effects
While Florfenicol is generally well-tolerated, potential side effects may include:

Injection Site Reactions:
Swelling or mild pain at the site.
Gastrointestinal Effects:
Reduced appetite or diarrhea (rare). Florfarma 30 for cattles
Liver and Kidney Strain:
Use with caution in animals with pre-existing hepatic or renal conditions.
Contraindications

Lactating Animals:

Not approved for use in dairy animals producing milk for human consumption.
Hypersensitivity:
Do not use in animals allergic to florfenicol.
Severely Debilitated Animals:
Avoid use in animals with severe liver or kidney dysfunction.
Precautions
Species-Specific Use:
Only use in animals for which the product is approved.
Proper Injection Technique:
Avoid overloading injection sites.
Avoid Overuse:
Overuse can lead to bacterial resistance. Florfarma 30 for cattles
Environmental Safety:
Dispose of unused product and containers in accordance with local regulations.
Storage
Store at room temperature (15°C–25°C).
Protect from light and freezing.
Shake well before use.
Available Forms
Injectable solutions are the most common formulation, typically in vials of 100 mL or 250 mL.

Key Points

Florfarma 30 is a highly effective broad-spectrum antibiotic for managing bacterial infections in livestock.
Administer under veterinary guidance to ensure proper dosage, usage, and compliance with withdrawal periods.
Overuse or misuse can contribute to antimicrobial resistance, which is a growing global concern.