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Hyaluronate sodium injection

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Given to horses intra-articularly in small and medium size joints (carpal, fetlock). In the treatment of largers joints (hock), the dosage is 4ml (40mg). The treatment may be repeated at weekly intervals for a total of 3 treatments.

Buy sodium hyaluronate injection for horses

Buy sodium hyaluronate injection for horses is a veterinary medication used to treat joint dysfunction and osteoarthritis in horses. The two primary formulations available are Legend (for intravenous use) and Hylartin V (for intra-articular use), both providing therapeutic hyaluronic acid for different administration routes and treatment approaches.

Available Products

Legend Injectable Solution

LEGEND Injectable Solution is indicated in the treatment of joint dysfunction of the carpus or fetlock in horses due to non-infectious synovitis associated with equine osteoarthritis. Each mL contains 10 mg hyaluronate sodium, 8.5 mg sodium chloride, 0.223 mg sodium phosphate dibasic, and other buffering agents.

Hylartin V

2 mL (20 mg) of HYLARTIN® V given to horses intra-articularly in small and medium size joints (carpal, fetlock). In the treatment of larger joints (hock), the dosage is 4 (40 mg). Buy sodium hyaluronate injection for horses

Mechanism of Action

Physiological Function:

Hyaluronic acid is a naturally occurring component of synovial fluid that provides:

Lubrication: Reduces friction between joint surfaces

Viscosupplementation: Restores normal synovial fluid viscosity

Anti-inflammatory Effects: Systemic hyaluronic acid (HA) is injected to horses routinely as a joint anti-inflammatory

Cartilage Protection: Supports cartilage metabolism and health

Buy sodium hyaluronate injection for horses Clinical Benefits:

This advanced FDA-approved injectable solution replenishes synovial fluid and helps restore normal joint function in horses with osteoarthritis.

Clinical Indications

Primary Uses:

Both formulations target:

Joint Dysfunction: Specifically carpus and fetlock joint problems

Non-infectious Synovitis: Inflammation of joint lining

Equine Osteoarthritis: Equine osteoarthritis can happen in any age and any discipline due to everyday wear and tear

Performance Enhancement: Maintaining joint health in athletic horses

Additional Applications:

Research has explored use for:

Tendon Injuries: Two (2) ml of sodium hyaluronate (treatment group) or 2 ml of saline (placebo) was given as a single injection into the center of the superficial flexor tendon lesion

Systemic Anti-inflammatory Effects: To gain insight into the effects of HA on skeletal muscle, adult Thoroughbred geldings (n = 6) were injected with a commercial HA product weekly for 3 weeks

Buy sodium hyaluronate injection for horses Dosage and Administration

Legend (Intravenous):

4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.

Administration Protocol:

Dose: 4 mL (40 mg) per treatment

Route: Intravenous injection into jugular vein

Frequency: Weekly intervals

Course: Maximum of 3 treatments

Technique: Slow IV injection with aseptic technique

Hylartin V (Intra-articular):

Given to horses intra-articularly in small and medium size joints (carpal, fetlock). In the treatment of largers joints (hock), the dosage is 4ml (40mg). The treatment may be repeated at weekly intervals for a total of 3 treatments.

Joint-Specific Dosing:

Small/Medium Joints (carpal, fetlock): 2 mL (20 mg)

Large Joints (hock): 4 mL (40 mg)

Frequency: Weekly intervals

Course: Up to 3 treatments maximum

Technique: Sterile intra-articular injection Buy sodium hyaluronate injection for horses

Safety Profile

Clinical Studies:

In an acute toxicity study in horses, HYLARTIN® V was injected intra-articularly at dosages corresponding to five times the recommended dose per animal (200 mg total). In a sub-acute study, horses were injected intra-articularly with the recommended dose per joint (20 mg) at weekly intervals

Research Findings:

The horses (n = 6) were injected with 40 mg of sodium hyaluronate purified from the capsule of Streptococcus spp. (HA; Legend, Boehringer Ingelheim, Duluth, GA, USA) into the jugular vein each week for 3 weeks, according to the manufacturer’s recommendations.

Clinical Efficacy

Treatment Outcomes:

The Legend horses showed obvious benefit. Treatment began on day 13 after surgery, continuing weekly for three treatments. Values were comparable to a normal joint, and treated horses experienced less lameness.

Research Applications:

Studies have evaluated hyaluronate sodium for various equine conditions, demonstrating effectiveness in:

Reducing joint inflammation

Improving lameness scores

Supporting post-surgical recovery

Maintaining joint health in performance horses

Professional Administration

Buy sodium hyaluronate injection for horses Veterinary Requirements:

Both formulations require:

Prescription: Veterinary prescription required

Professional Administration: Proper injection technique essential

Sterile Technique: Aseptic administration protocols

Patient Assessment: Pre-treatment evaluation of joint condition

Monitoring: Post-injection observation for adverse reactions

Administration Considerations:

Legend: Requires IV access and slow injection technique

Hylartin V: Requires sterile joint entry and proper needle placement

Site Preparation: Thorough cleaning and disinfection

Post-injection Care: Activity restriction and monitoring as indicated

Treatment Scheduling

Typical Protocol:

Initial Assessment: Complete lameness and joint evaluation

First Treatment: Baseline injection (IV or intra-articular)

Weekly Follow-up: Second treatment at 7-day interval

Final Treatment: Third injection completing the series

Response Evaluation: Assessment of treatment efficacy

Duration Considerations:

Maximum Treatments: 3 injections per series

Re-treatment: Additional series may be considered based on clinical response

Maintenance: Some horses benefit from periodic re-treatment

Professional Monitoring: Ongoing veterinary assessment throughout treatment Buy sodium hyaluronate injection for horses

Storage and Handling

Product Storage:

Refrigerated storage typically required

Protect from light and temperature extremes

Use aseptic technique during preparation

Single-use vials to prevent contamination

Follow manufacturer’s storage guidelines

Hyaluronate Sodium Injection for horses

Equine joint injection therapy

Hyaluronic acid injection for horses

Veterinary joint supplement injectable

Regulatory Status

Both Legend and Hylartin V are FDA-approved veterinary medications specifically indicated for treating joint dysfunction in horses, representing established therapeutic options with proven safety and efficacy profiles in equine medicine.

Hyaluronate sodium injections provide valuable therapeutic options for managing equine joint health, offering both systemic (Legend) and local (Hylartin V) treatment approaches for addressing osteoarthritis and joint dysfunction in horses across various disciplines and age groups.

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