Buy sodium hyaluronate injection for horses
Buy sodium hyaluronate injection for horses is a veterinary medication used to treat joint dysfunction and osteoarthritis in horses. The two primary formulations available are Legend (for intravenous use) and Hylartin V (for intra-articular use), both providing therapeutic hyaluronic acid for different administration routes and treatment approaches.
Available Products
Legend Injectable Solution
LEGEND Injectable Solution is indicated in the treatment of joint dysfunction of the carpus or fetlock in horses due to non-infectious synovitis associated with equine osteoarthritis. Each mL contains 10 mg hyaluronate sodium, 8.5 mg sodium chloride, 0.223 mg sodium phosphate dibasic, and other buffering agents.
Hylartin V
2 mL (20 mg) of HYLARTIN® V given to horses intra-articularly in small and medium size joints (carpal, fetlock). In the treatment of larger joints (hock), the dosage is 4 (40 mg). Buy sodium hyaluronate injection for horses
Mechanism of Action
Physiological Function:
Hyaluronic acid is a naturally occurring component of synovial fluid that provides:
Lubrication: Reduces friction between joint surfaces
Viscosupplementation: Restores normal synovial fluid viscosity
Anti-inflammatory Effects: Systemic hyaluronic acid (HA) is injected to horses routinely as a joint anti-inflammatory
Cartilage Protection: Supports cartilage metabolism and health
Buy sodium hyaluronate injection for horses Clinical Benefits:
This advanced FDA-approved injectable solution replenishes synovial fluid and helps restore normal joint function in horses with osteoarthritis.
Clinical Indications
Primary Uses:
Both formulations target:
Joint Dysfunction: Specifically carpus and fetlock joint problems
Non-infectious Synovitis: Inflammation of joint lining
Equine Osteoarthritis: Equine osteoarthritis can happen in any age and any discipline due to everyday wear and tear
Performance Enhancement: Maintaining joint health in athletic horses
Additional Applications:
Research has explored use for:
Tendon Injuries: Two (2) ml of sodium hyaluronate (treatment group) or 2 ml of saline (placebo) was given as a single injection into the center of the superficial flexor tendon lesion
Systemic Anti-inflammatory Effects: To gain insight into the effects of HA on skeletal muscle, adult Thoroughbred geldings (n = 6) were injected with a commercial HA product weekly for 3 weeks
Buy sodium hyaluronate injection for horses Dosage and Administration
Legend (Intravenous):
4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.
Administration Protocol:
Dose: 4 mL (40 mg) per treatment
Route: Intravenous injection into jugular vein
Frequency: Weekly intervals
Course: Maximum of 3 treatments
Technique: Slow IV injection with aseptic technique
Hylartin V (Intra-articular):
Given to horses intra-articularly in small and medium size joints (carpal, fetlock). In the treatment of largers joints (hock), the dosage is 4ml (40mg). The treatment may be repeated at weekly intervals for a total of 3 treatments.
Joint-Specific Dosing:
Small/Medium Joints (carpal, fetlock): 2 mL (20 mg)
Large Joints (hock): 4 mL (40 mg)
Frequency: Weekly intervals
Course: Up to 3 treatments maximum
Technique: Sterile intra-articular injection Buy sodium hyaluronate injection for horses
Safety Profile
Clinical Studies:
In an acute toxicity study in horses, HYLARTIN® V was injected intra-articularly at dosages corresponding to five times the recommended dose per animal (200 mg total). In a sub-acute study, horses were injected intra-articularly with the recommended dose per joint (20 mg) at weekly intervals
Research Findings:
The horses (n = 6) were injected with 40 mg of sodium hyaluronate purified from the capsule of Streptococcus spp. (HA; Legend, Boehringer Ingelheim, Duluth, GA, USA) into the jugular vein each week for 3 weeks, according to the manufacturer’s recommendations.
Clinical Efficacy
Treatment Outcomes:
The Legend horses showed obvious benefit. Treatment began on day 13 after surgery, continuing weekly for three treatments. Values were comparable to a normal joint, and treated horses experienced less lameness.
Research Applications:
Studies have evaluated hyaluronate sodium for various equine conditions, demonstrating effectiveness in:
Reducing joint inflammation
Improving lameness scores
Supporting post-surgical recovery
Maintaining joint health in performance horses
Professional Administration
Buy sodium hyaluronate injection for horses Veterinary Requirements:
Both formulations require:
Prescription: Veterinary prescription required
Professional Administration: Proper injection technique essential
Sterile Technique: Aseptic administration protocols
Patient Assessment: Pre-treatment evaluation of joint condition
Monitoring: Post-injection observation for adverse reactions
Administration Considerations:
Legend: Requires IV access and slow injection technique
Hylartin V: Requires sterile joint entry and proper needle placement
Site Preparation: Thorough cleaning and disinfection
Post-injection Care: Activity restriction and monitoring as indicated
Treatment Scheduling
Typical Protocol:
Initial Assessment: Complete lameness and joint evaluation
First Treatment: Baseline injection (IV or intra-articular)
Weekly Follow-up: Second treatment at 7-day interval
Final Treatment: Third injection completing the series
Response Evaluation: Assessment of treatment efficacy
Duration Considerations:
Maximum Treatments: 3 injections per series
Re-treatment: Additional series may be considered based on clinical response
Maintenance: Some horses benefit from periodic re-treatment
Professional Monitoring: Ongoing veterinary assessment throughout treatment Buy sodium hyaluronate injection for horses
Storage and Handling
Product Storage:
Refrigerated storage typically required
Protect from light and temperature extremes
Use aseptic technique during preparation
Single-use vials to prevent contamination
Follow manufacturer’s storage guidelines
Hyaluronate Sodium Injection for horses
Equine joint injection therapy
Hyaluronic acid injection for horses
Veterinary joint supplement injectable
Regulatory Status
Both Legend and Hylartin V are FDA-approved veterinary medications specifically indicated for treating joint dysfunction in horses, representing established therapeutic options with proven safety and efficacy profiles in equine medicine.
Hyaluronate sodium injections provide valuable therapeutic options for managing equine joint health, offering both systemic (Legend) and local (Hylartin V) treatment approaches for addressing osteoarthritis and joint dysfunction in horses across various disciplines and age groups.
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