Finadyne

finadyne inyectable​ is the brand name for flunixin meglumine, a potent nonsteroidal anti-inflammatory drug (NSAID) commonly used in veterinary medicine. It is primarily utilized for its analgesic, anti-inflammatory, and antipyretic (fever-reducing) properties in livestock and horses. It is particularly valued for managing pain and inflammation associated with musculoskeletal disorders, colic, and endotoxemia finadyne precio​.

Active Ingredient
Flunixin Meglumine: A non-selective NSAID that inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins involved in pain, inflammation, and fever.
Indications (Uses)
Finadyne is approved for use in several species, including horses, cattle, and pigs. Common indications include:

In Horses:

Relief of pain and inflammation associated with musculoskeletal disorders, such as:
Laminitis
Tendonitis
Arthritis
Treatment of colic to relieve abdominal pain.
Reduction of fever associated with infections and endotoxemia.
In Cattle:
Treatment of acute mastitis.
Reduction of fever and inflammation in bovine respiratory diseases (BRD).
Supportive therapy in endotoxemia caused by infections.
In Pigs:
Management of pain and inflammation associated with infectious diseases, particularly in respiratory conditions.

Dosage and Administration

General Guidelines:
Finadyne is available as an injectable solution, oral paste, and granules.
It is typically administered via intravenous (IV) or intramuscular (IM) injection, depending on the condition being treated.
Horses:
Dose: 1.1 mg/kg body weight.
Route: IV injection for colic and musculoskeletal pain.
Frequency: Once daily for up to 5 consecutive days, as needed.
Oral Paste: May also be used for prolonged treatment under veterinary guidance.
Cattle:
Dose: 2.2 mg/kg body weight.
Route: IV injection.
Frequency: Once daily for up to 3 days for respiratory conditions or mastitis.

Pigs:

Dose: 2.2 mg/kg body weight.
Route: IM injection.
Frequency: Once daily for 1-3 days.
Important Note:
Always follow the specific dosing recommendations provided by a veterinarian, as dosages may vary based on species, condition, and product formulation.

Pharmacokinetics
Onset of Action: Rapid, with effects typically seen within 2 hours after injection.
Duration: Provides relief for 12-24 hours, depending on the condition being treated.
Metabolism: Metabolized by the liver. finadyne inyectable​
Excretion: Primarily via urine.
Withdrawal Periods
For animals intended for human consumption (e.g., cattle and pigs), observe strict withdrawal periods:

finadyne precio​

Meat (Cattle): 7-10 days after the last injection, depending on the formulation.
Milk (Cattle): 36-48 hours after the last treatment.
Meat (Pigs): 21 days after treatment. Check local regulations, as withdrawal times can vary.
Side Effects
While generally safe when used as directed, side effects can occur, particularly with prolonged or high-dose use:

Gastrointestinal Issues:
Stomach ulcers.
Colitis (inflammation of the colon).
Kidney Damage:
Use with caution in dehydrated animals.
Injection Site Reactions:
Local swelling or pain after IM injection. finadyne precio​
Allergic Reactions:
Rare but possible.
Blood Coagulation Issues:
Rare interference with blood clotting.
Contraindications

Pre-existing Conditions:

Avoid in animals with kidney or liver disease.
Use with caution in dehydrated or hypovolemic animals. finadyne inyectable​
Concurrent NSAID or Corticosteroid Use:
Combining with other anti-inflammatory drugs increases the risk of gastrointestinal ulcers and kidney damage.
Pregnant or Lactating Animals:
Use only under veterinary supervision.
Precautions
Ensure proper hydration during treatment.
Do not exceed recommended doses or treatment duration.
Administer IV injections carefully to avoid accidental perivascular injection, which may cause tissue irritation.
Storage
Store at room temperature (15°C – 25°C).
Protect from light and freezing. finadyne precio​
Discard unused portions as per manufacturer recommendations.
Available Forms
Injectable Solution: Commonly in 50 mg/mL concentration (e.g., 100 mL or 250 mL vials).
Oral Paste: Flavored paste for ease of administration in horses.
Granules: For mixing with feed in some species.

Key Notes

Finadyne is a prescription-only medication; it should be used under veterinary supervision.
Misuse or overuse can lead to serious complications, including ulcers, kidney damage, or adverse drug reactions.
Regular monitoring of treated animals is recommended, especially for long-term use. finadyne inyectable​