Gonadorelin injection

Gonadorelin injection is a synthetic form of gonadotropin-releasing hormone (GnRH), which is naturally secreted by the hypothalamus in mammals. It is widely used in veterinary medicine for the regulation of reproductive function, particularly in cattle, horses, and other livestock. gonadorelin vs hcg​, gonadorelin for men

Key Properties
Mechanism of Action:

Gonadorelin stimulates the anterior pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH). gonadorelin vs hcg​
These hormones are essential for:
Ovulation.
Follicular development. Gonadorelin injection
Corpus luteum formation and function.
Synthetic Analog:

Gonadorelin is a short-acting GnRH analog, mimicking the body’s natural hormone, making it highly effective for clinical use.

Uses in Veterinary Medicine

Cattle:

Treatment of Ovarian Cysts:
Gonadorelin induces luteinization or ovulation of follicular cysts.
Estrus Synchronization:
Used as part of timed artificial insemination (AI) protocols (e.g., Ovsynch programs).
Anovulation or Delayed Ovulation:
Stimulates ovulation in cows with delayed estrus.
Horses:

Induction of Ovulation:
Administered during estrus to time ovulation for breeding or artificial insemination.
Support for Breeding Programs:
Improves reproductive efficiency in mares. gonadorelin for men
Sheep, Goats, and Other Livestock:

Promotes synchronized breeding and ovulation in species with similar hormonal cycles.
Other Potential Uses:

Testicular Function Testing:
Used to evaluate hypothalamic-pituitary-gonadal axis integrity in some animals.
Induction of Estrus:
Used off-label in certain species to stimulate estrus in breeding programs. Gonadorelin injection
Dosage Guidelines
Cattle:

Ovarian cysts: 100–250 µg intramuscularly (IM) or subcutaneously (SC).
Ovsynch Protocol:
100 µg IM on Day 0 (GnRH injection).
Prostaglandin F2α on Day 7.
Second GnRH injection (100 µg IM) on Day 9.
Timed AI approximately 16–20 hours after the second GnRH injection.
Horses:

Induction of ovulation: 50–100 µg IM or intravenously (IV) when a dominant follicle >35 mm is present.
Other Livestock (e.g., sheep, goats):

Doses range from 50–150 µg IM or SC, depending on species and intended use. gonadorelin for men
Onset and Duration
Onset of Action:
LH and FSH release occurs within minutes after injection. Gonadorelin injection
Duration:
Hormonal effects are short-lived, typically lasting 2–4 hours.
Side Effects

Common Side Effects:

Minimal to no side effects when used at recommended dosages.
Rare Side Effects:

Mild local irritation at the injection site.
Rare allergic reactions or hypersensitivity.
Contraindications and Precautions
Contraindications:

Not effective in animals with non-functional pituitary glands or hypothalamic damage.
Do not use in animals with known hypersensitivity to GnRH or its analogs. gonadorelin vs hcg​
Precautions:

Use cautiously in animals with unknown ovarian or reproductive conditions.
Avoid repeated or excessive dosing, as this may desensitize the pituitary to GnRH stimulation.
Use During Pregnancy:

Generally safe, but not typically indicated for use in pregnant animals. Gonadorelin injection
Drug Interactions
Prostaglandin F2α (PGF2α):
Often combined with prostaglandins in reproductive synchronization protocols.
Other Hormonal Treatments:
Can be used alongside FSH or human chorionic gonadotropin (hCG) for advanced breeding management.
Storage Instructions
Store at 2–8°C (refrigerated).
Protect from light and do not freeze.
Once reconstituted, use within the recommended time frame (check product-specific guidelines).
Advantages of Gonadorelin

High Specificity:

Directly targets the hypothalamic-pituitary axis, making it effective for reproductive management.
Short Half-Life:
Reduces the risk of prolonged hormonal imbalances or side effects. gonadorelin vs hcg​
Versatile:
Can be used across a variety of species and reproductive protocols.
Popular Trade Names
Cystorelin (Merial)
Factrel (Zoetis)
Fertagyl (Intervet)
Ovacyst (Bayer)

Buy Gonadorelin

Gonadorelin injection is a vital tool in veterinary reproduction for estrus synchronization, ovarian cyst treatment, and induction of ovulation. gonadorelin for men
Proper administration and adherence to dosage protocols are crucial for optimal results.
It is safe, widely available, and highly effective when used under veterinary guidance.