Linco Spectin Injection

Linco-Spectin Injection is a broad-spectrum antibiotic combination used in veterinary medicine to treat various bacterial infections in animals. It combines two powerful antibiotics: Lincomycin and Spectinomycin, offering both bacteriostatic and bactericidal effects. Lincomycin Spectinomycin for Veterinary Use, Lincomycin Spectinomycin, Linco Spectin for Poultry, Lincomycin Spectinomycin for Livestock

1. Composition
Lincomycin (as hydrochloride): A lincosamide antibiotic effective against Gram-positive bacteria and some mycoplasmas.

Spectinomycin (as sulfate): An aminocyclitol antibiotic mainly active against Gram-negative bacteria and Mycoplasma spp.

2. Mechanism of Action
Lincomycin inhibits protein synthesis by binding to the 50S ribosomal subunit, blocking peptide chain elongation.

Spectinomycin inhibits protein synthesis at the 30S ribosomal subunit, preventing bacterial replication.

Together, they cover a wide range of Gram-positive and Gram-negative organisms, as well as Mycoplasma spp.

3. Indications (Uses)
Linco-Spectin is primarily used in swine, poultry, and sometimes calves, for:

Lincomycin Spectinomycin for Veterinary Use

Swine:
Swine dysentery (Brachyspira hyodysenteriae)

Mycoplasma pneumonia (Mycoplasma hyopneumoniae)

Colibacillosis (E. coli infections)

Enteritis due to Clostridium spp. or mixed infections

Poultry:
Chronic respiratory disease (CRD) caused by Mycoplasma gallisepticum and Mycoplasma synoviae

Colibacillosis

Air sacculitis

Synovitis

Enteric infections

Calves and Other Young Animals (off-label use in some regions):
Respiratory infections

Enteric bacterial infections

Septicemia

Linco Spectin Injection

Dosage and Administration
Note: Always follow your veterinarian’s dosage recommendations.

General Doses (may vary by product/region):
Swine:

IM Injection: 1 ml per 10 kg body weight once daily for 3–5 days.

Poultry (usually administered via drinking water or injection in rare cases):

Injection: 10–20 mg/kg body weight, depending on severity and species.

Calves (off-label):

IM Injection: 1 ml per 10–15 kg body weight, once daily for 3–5 days.

Route:

Intramuscular (IM) injection is the most common.

Can also be administered subcutaneously or intravenously under strict veterinary guidance.

5. Contraindications
Do not use in animals with hypersensitivity to lincomycin or spectinomycin.

Not recommended for ruminants (e.g., adult cattle, sheep, goats) with a functioning rumen, due to risk of gut flora disruption.

Linco Spectin for Poultry

Do not use in rabbits, hamsters, or guinea pigs – high risk of fatal enteritis.

6. Precautions
Use under veterinary supervision only.

Maintain strict withdrawal periods for meat or eggs.

Avoid use in animals with renal or liver impairment unless advised by a vet.

Observe animals for signs of allergic reaction or gastrointestinal upset.

7. Side Effects
Local irritation or swelling at injection site

Occasional diarrhea or gastrointestinal disturbance

Allergic reactions (rare)

Long-term use may lead to antibiotic resistance

8. Withdrawal Periods
(Always verify based on local regulations and product label):

Linco Spectin Injection

Meat:

Swine: ~21 days

Poultry: ~7 days

Eggs: Not for use in laying hens producing eggs for human consumption

Lincomycin Spectinomycin

Storage
Store in a cool, dry place (typically below 25°C).

Protect from light and freezing.

Use within a specified period after first opening the vial (e.g., 28 days).

10. Product Forms & Brands
Linco-Spectin is available under various veterinary pharmaceutical brands, such as:

Linco-Spectin 100 Injection

Linco-Spectin Injectable Solution (Zoetis)

Lincomycin + Spectinomycin combo from generic manufacturers

Available in 50 ml, 100 ml, or 250 ml multidose vials. Linco Spectin for Poultry

11. Summary of Benefits
Effective against respiratory and enteric infections
Combines two complementary antibiotics
Used in both prevention and treatment
Broad spectrum: covers Mycoplasma, Gram-positive, and Gram-negative pathogens

Linco Spectin Injection

Conclusion
Linco-Spectin Injection is a valuable tool in veterinary medicine, especially in managing respiratory and enteric infections in swine and poultry. Its dual antibiotic composition provides wide-spectrum action and rapid clinical improvement. Proper dosing, compliance with withdrawal periods, and professional veterinary oversight are critical for safe and effective use. Lincomycin Spectinomycin