Lincomix 300 for Poultry

Lincomix 300 for Poultry is a sterile injectable solution containing lincomycin hydrochloride at a concentration of 300 mg/mL. It is primarily used in poultry and livestock to treat Gram-positive bacterial infections and Mycoplasma-related respiratory diseases. Lincomycin 300 for Livestock, Lincomix 300 Dosage for Animals, Lincomycin 300 mg/mL Solution

Composition

Active Ingredient: Lincomycin hydrochloride

Concentration: 300 mg/mL

Form: Injectable solution

Packaging: 50 mL, 100 mL, 250 mL, or 500 mL vials

Mechanism of Action

Lincomycin is a lincosamide antibiotic that acts by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit, blocking peptide chain elongation.

Spectrum:

Gram-positive bacteria: Streptococcus spp., Staphylococcus spp., Clostridium spp.

Mycoplasma spp. (especially important in poultry)

Anaerobic bacteria

It is bacteriostatic, but may exhibit bactericidal activity at high concentrations or against highly susceptible organisms.

Lincomix 300 Dosage for Animals

Indications
1. Poultry (Chickens, Turkeys) Lincomix 300 for Poultry

Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum

Air sacculitis

Mycoplasma synoviae infections

Synovitis (infectious arthritis)

Enteritis due to susceptible organisms

2. Livestock (Swine, Calves, Sheep, Goats)

Mycoplasmal pneumonia (enzootic pneumonia)

Arthritis caused by Mycoplasma hyosynoviae

Swine dysentery

Bacterial enteritis

Clostridial infections Lincomix 300 Dosage for Animals

Foot rot and wound infections in ruminants (off-label)

Dosage and Administration

Note: Dosages may vary by country, species, and veterinary guidance.

Lincomix 300 for Poultry

Swine:

IM injection:

5 mg/lb (11 mg/kg) body weight once daily

Example: 1 mL per 60 lb body weight

Duration: 3 to 7 days depending on the condition

Calves, Sheep, Goats (off-label use):

IM or SC injection:

10 mg/kg body weight daily

Duration: 3 to 5 days

Poultry:

Water-soluble forms are preferred, but injectable Lincomix 300 may be used off-label via IM injection in individual birds or for special treatment cases:

5–15 mg/kg body weight once daily IM

Practical in valuable breeding stock or show birds

Contraindications

Not for use in rabbits, hamsters, guinea pigs, or horses – may cause fatal enteritis.

Do not administer to animals with known hypersensitivity to lincomycin. Lincomix 300 for Poultry

Use caution in animals with impaired liver or kidney function.

Lincomycin 300 mg/mL Solution

Warnings & Precautions

Do not use in animals intended for milk production (unless specifically labeled for such use).

Use with caution in pregnant or breeding animals – safety data may be limited.

Avoid prolonged use — may promote resistance or cause gastrointestinal upset.

Ensure clean injection technique to prevent abscess formation.

Withdrawal Periods

Always confirm with product labeling and local regulatory guidelines.

Lincomycin 300 for Livestock

Swine:

Meat: 48 hours

Cattle/Calves (off-label):

Meat: Up to 7 days (varies by country)

Poultry (off-label injection):

Meat: Typically 24–48 hours

Milk: Not approved for use in lactating dairy animals producing milk for human consumption

Storage & Handling

Store at 15°C to 30°C (59°F to 86°F)

Do not freeze

Use within 28 days of first vial puncture (multi-dose vial)

Shake well before use if instructed Lincomix 300 for Poultry

Benefits of Lincomix 300

Potent against Mycoplasma infections in poultry and pigs

Treats respiratory and joint infections effectively

Fast-acting, once-daily dosing

Useful in early intervention or outbreak control

Potential Side Effects

Mild swelling or pain at injection site

Occasional diarrhea in sensitive animals

Rare allergic reactions (e.g., hives, respiratory distress)

Summary