long range injection

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LONGRANGE (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in

long range injection

Long Range injection is a long-acting injectable dewormer for beef cattle, containing eprinomectin, a macrocyclic lactone from the avermectin class. It provides up to 100–150 days of parasite control with a single dose.

The unique extended-release formulation is achieved using TheraPhase™ technology, which ensures gradual release over time.

Indications (Uses)

Approved for use in beef cattle to treat and control both internal and external parasites, including:

Gastrointestinal Roundworms (adults and larvae):

Ostertagia ostertagi (Brown stomach worm)

Haemonchus placei (Barber pole worm)

Trichostrongylus axei

Cooperia spp.

Oesophagostomum radiatum (Nodular worm)

Bunostomum phlebotomum (Hookworm)

Lungworms:

Dictyocaulus viviparus

External Parasites:

Horn flies (Haematobia irritans)

Sucking lice

Mange mites (Sarcoptes, Chorioptes)

Mechanism of Action

Eprinomectin binds to glutamate-gated chloride channels in the nerve and muscle cells of parasites, increasing chloride ion permeability and causing paralysis and death of the parasite.

The extended-release technology creates a bimodal plasma concentration curve:

First peak: immediate action

Second peak: sustained release after ~70 days, extending protection up to ~150 days

Dosage and Administration

Dose: 1 mL per 50 kg (110 lbs) body weight
(equivalent to 1.0 mg eprinomectin/kg)

Route: Subcutaneous injection
Administered behind the shoulder using sterile technique

Animal Weight Dose (mL)
100 kg 2 mL
250 kg 5 mL
500 kg 10 mL

Do not administer more than 10 mL per injection site

Duration of Action

Parasite Protection Duration
Ostertagia ostertagi Up to 120–150 days
Cooperia spp. ~100 days
Haemonchus placei ~100 days
Trichostrongylus axei ~100 days
Dictyocaulus viviparus ~100 days
Horn flies ~100–130 days

long range injection for cattle

Contraindications & Warnings

Do NOT use in dairy cattle, including dry cows or replacement heifers, due to milk residue risk

Not for use in calves intended for veal

Avoid repeated use to prevent parasite resistance

Do not inject intramuscularly or intravenously

Use sterile equipment to avoid injection site reactions

Withdrawal Period

Meat withdrawal: 48 days

Milk withdrawal: Not established – Do not use in lactating dairy cows

Side Effects

Generally well tolerated. Rare adverse effects may include:

Mild injection site swelling

Occasional lethargy or discomfort

Storage and Handling

Store below 25°C (77°F)

Protect from light and freezing

Use within 90 days of opening the vial

Shake well before use

Resistance and Strategic Deworming

To reduce the risk of anthelmintic resistance:

Use targeted deworming protocols

Avoid unnecessary retreatment

Combine with pasture management strategies

Rotate classes of dewormers (e.g., benzimidazoles, levamisole)

Summary Table

Feature Description
Drug Name LongRange®
Active Ingredient Eprinomectin (50 mg/mL)
Class Macrocyclic lactone (avermectin)
Route Subcutaneous (SC)
Dose 1 mL/50 kg BW
Duration Up to 100–150 days
Species Beef cattle only
Milk Withdrawal Not permitted (zero tolerance)
Meat Withdrawal 48 days
Main Uses Long-acting internal and external parasite control
Special Tech TheraPhase™ extended-release technology

long range injection for cattle

LongRange is ideal for range cattle, reducing the need for frequent handling.

Consult a veterinarian for region-specific parasite control recommendations.

Not to be confused with short-acting injectables like Ivomec, Dectomax, or Noromectin.

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