Fertagyl

fertagyl injection for cattle​ is a veterinary pharmaceutical product containing gonadorelin, a synthetic analog of gonadotropin-releasing hormone (GnRH). It is used in livestock for reproductive management, particularly to address fertility issues, synchronize estrus cycles, and enhance breeding efficiency. fertagyl preço

Composition:
Gonadorelin diacetate tetrahydrate: The active ingredient equivalent to 50 mcg/mL of gonadorelin.
Mechanism of Action:
Fertagyl stimulates the release of two critical reproductive hormones from the anterior pituitary gland:
Luteinizing Hormone (LH): Triggers ovulation and corpus luteum formation.
Follicle-Stimulating Hormone (FSH): Supports follicular development.
By inducing these hormones, it helps regulate and synchronize the reproductive cycle.
Indications:

Fertagyl is used in various reproductive applications, including:

Synchronization of Estrus/Ovulation:
Commonly used in Timed Artificial Insemination (TAI) programs.
Treatment of Ovarian Dysfunction:
For conditions like follicular cysts in cows, which can disrupt normal cycling.
Improvement of Conception Rates:
Used in breeding protocols to optimize ovulation timing.
Support for Embryo Transfer Programs:
Ensures precise synchronization of donor and recipient animals. fertagyl preço
Target Species:
Cattle: Dairy cows, beef cows, and heifers.
Other species: Off-label use in other animals, such as horses, may be considered under veterinary guidance.

Dosage:

The dosage of Fertagyl depends on the reproductive protocol being followed and the specific condition being treated. Below is the general dosage information for cattle, the primary target species:
The typical dosage and administration depend on the protocol used:

Cattle:
Dose: 2 mL (equivalent to 100 mcg of gonadorelin) per animal.
Administered intramuscularly (IM) or intravenously (IV).
Estrus Synchronization Protocols:
Often used as part of a GnRH-PGF2α-GnRH protocol (e.g., Ovsynch):
Administer Fertagyl on Day 0 to induce ovulation.
Administer prostaglandin (PGF2α) on Day 7 to regress the corpus luteum.
Administer another dose of Fertagyl 48 hours after PGF2α for final ovulation induction.

Specific Protocols:

1. Estrus Synchronization (Ovsynch Program):
Day 0: Administer 2 mL of Fertagyl to induce ovulation of the dominant follicle.
Day 7: Administer prostaglandin (PGF2α) to regress the corpus luteum.
Day 9: Administer another 2 mL of Fertagyl to induce ovulation of the new follicle. fertagyl preço
Day 10: Perform artificial insemination (AI) approximately 16-24 hours after the second Fertagyl injection.
2. Treatment of Ovarian Follicular Cysts:
Administer 2 mL (100 mcg) as a single dose intramuscularly (IM) or intravenously (IV).
Repeat as recommended by your veterinarian based on the animal’s response.
3. Improving Conception Rates in Breeding:
Administer 2 mL (100 mcg) at the time of breeding or in conjunction with other synchronization protocols.
Administration:
Administer via intramuscular (IM) or intravenous (IV) injection.
Follow strict aseptic techniques to prevent infections. fertagyl injection for cattle​

Storage:

Store at 2°C to 8°C (36°F to 46°F).
Protect from light and freezing.
Keep the container sealed to maintain sterility.
Precautions:
Species-specific use:
Designed for cattle; consult a veterinarian before using on other species.
Proper handling:
Avoid accidental self-injection; GnRH analogs can affect human reproductive hormones.
Health status:
Do not use in animals with severe systemic infections or reproductive tract injuries.
Side Effects:
Minimal side effects when used as directed.
Rarely, mild swelling or irritation at the injection site may occur. fertagyl injection for cattle​
Overuse can lead to hormonal imbalances or unintended effects.

Benefits:

Enhances reproductive efficiency in dairy and beef operations. fertagyl preço
Reduces the interval between calving and conception.
Facilitates herd management by synchronizing estrus cycles.
Usage Considerations:
Ensure the animal is not already pregnant before administration to avoid complications.
Follow the recommended dosage and protocol closely for optimal results.
Veterinary consultation is essential for tailored reproductive strategies.

Summary:

Fertagyl is a reliable tool for reproductive management in cattle, particularly in estrus synchronization and treatment of ovarian dysfunction. Its use in timed breeding protocols helps improve conception rates and streamline herd reproductive performance. Always consult a veterinarian to ensure safe and effective use. fertagyl preço