loxicom 100ml

loxicom 100ml is a non-steroidal anti-inflammatory drug (NSAID) used to treat:

Pain

Inflammation

Fever

It works by selectively inhibiting the cyclooxygenase-2 (COX-2) enzyme more than COX-1, which helps reduce inflammation and pain while minimizing gastrointestinal side effects.

Indications (Uses)

Dogs:

Osteoarthritis and musculoskeletal pain

Post-operative pain (e.g., after soft tissue or orthopedic surgery)

Cats:

Post-operative pain (e.g., spaying, neutering)

Acute musculoskeletal disorders

Chronic kidney-related osteoarthritis (in some countries – off-label)

Horses:

Relief of inflammation and pain associated with musculoskeletal disorders and colic

Cattle and Pigs:

Respiratory disease

Diarrhea (calf scours)

Post-operative pain (e.g., dehorning, castration, surgery)

Mechanism of Action

Meloxicam blocks prostaglandin synthesis by inhibiting COX-2, which is primarily involved in inflammation, while sparing COX-1, which protects the gastrointestinal tract and kidneys.

This leads to:

Reduced inflammation

Decreased pain sensitivity

Lowered fever

loxicom 100ml Dosage and Administration

Dogs:

Oral suspension:

Initial: 0.2 mg/kg, then 0.1 mg/kg daily

Given with or after food

Injection:

0.2 mg/kg SC or IV once, followed by oral maintenance

Cats:

Injection:

0.3 mg/kg SC as a single dose

Oral suspension:

0.05 mg/kg once daily (use caution, especially long-term)

Horses:

Injection: 0.6 mg/kg IV once daily

Oral paste: 0.6 mg/kg PO daily (often up to 14 days)

Cattle:

Injection: 0.5 mg/kg IV or SC once

Pigs:

Injection: 0.4 mg/kg IM once

 Always use species-specific formulations and dosing devices (syringes/spoons). Never use dog formulations in cats unless directed by a veterinarian.

Contraindications

Known hypersensitivity to meloxicam or other NSAIDs

Pre-existing gastric or intestinal ulcers

Kidney or liver disease

Dehydration, hypovolemia, or hypotension

Use in pregnant/lactating animals (unless approved by vet)

Do not use in animals under 6 weeks (dogs) or under 4 months (cats)

Side Effects

Common:

Vomiting

Diarrhea

Lethargy

Loss of appetite

Less Common but Serious:

GI ulcers or bleeding

Kidney toxicity

Liver enzyme elevation

Early discontinuation and supportive care are critical if adverse reactions occur.

Onset and Duration

Onset: Within 1–2 hours

Duration: 24 hours (once-daily dosing)

Withdrawal Periods (for food animals)

Always consult local regulations as withdrawal periods may vary by country or product variant. loxicom 100ml

Storage

Store at room temperature (typically below 25°C)

Do not freeze

Keep bottle tightly closed and use the measuring syringe provided

After opening:

Oral suspensions: Use within 6 months

Injectable: Use within 28 days

loxicom 100ml Summary Table

Clinical Insight

Well tolerated in most animals if used at appropriate dose and duration

Often used pre-emptively before surgery to control post-operative pain

Do not combine with steroids or other NSAIDs

In cats, long-term use is controversial and must be monitored closely loxicom 100ml