irap for horses

irap for horses or Interleukin-1 Receptor Antagonist Protein, is a biological treatment used primarily in equine medicine for the management of osteoarthritis and joint inflammation. It is a regenerative therapy that uses the animal’s own blood to produce anti-inflammatory proteins that inhibit interleukin-1 (IL-1), a key contributor to joint degeneration and pain. buy irap injection for horses, irap injections for horses, irap injections for horses cost, IRAP veterinary products

How Does IRAP Work?
IL-1 is a pro-inflammatory cytokine that promotes cartilage degradation, inflammation, and pain in joints.
IRAP therapy involves the extraction and processing of the animal’s blood, stimulating it to produce natural antagonists to IL-1.
The IRAP protein binds to IL-1 receptors, blocking IL-1 activity and reducing inflammation and tissue damage.
IRAP Production Process (Autologous Therapy)
Blood Collection:
Sterile blood is drawn into a specialized syringe containing chromium sulfate-coated beads.
Incubation:
The blood is incubated for 24 hours at 37°C to stimulate the production of IL-1 receptor antagonists, growth factors, and anti-inflammatory cytokines. irap for horses
Centrifugation:
The blood is centrifuged, and the serum rich in IRAP and growth factors is harvested.
Storage:
The serum can be stored frozen in aliquots for future injections.
Uses in Veterinary Medicine

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Osteoarthritis (OA) – most common use
Synovitis (joint inflammation)
Tendon and ligament injuries
Post-surgical joint therapy

Dogs:

Increasingly used for canine OA, especially in working dogs or pets with early joint disease
Administration & Dosage
Administered via intra-articular (IA) injection directly into the affected joint.
Typical protocol: irap for horses
1 injection every 7–10 days for 3–4 treatments. IRAP veterinary products
Repeat treatments may be done monthly or as needed based on clinical signs.
Volume per joint: Usually 2–5 mL, depending on joint size and species.
Benefits of IRAP Therapy
Drug-free treatment using autologous serum.
Reduces pain and inflammation without corticosteroids or NSAIDs.
Delays progression of osteoarthritis.
Can improve joint mobility and athletic performance.
Minimal risk of immune reaction or adverse effects.

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Side Effects and Precautions
Mild joint swelling or soreness post-injection (temporary).
As with any intra-articular injection, risk of infection (aseptic technique critical).
Not ideal for acute infections or septic joints.
No withdrawal time needed, as it’s drug-free (check local competition rules).
Storage and Handling
IRAP serum can be frozen in aliquots for long-term storage.
Must be thawed properly before use—do not refreeze once thawed.
Regulatory Status
IRAP therapy is widely accepted in equine sports medicine.
May be regulated or restricted in some racing jurisdictions or FEI competitions—always check specific rules.
Commercial Products / Systems irap injections for horses
Orthokine Vet IRAP
IRAP II System
Autologous Conditioned Serum (ACS) – generic term often used synonymously

Comparison to Similar Therapies

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irap for horses Therapy is a cutting-edge, natural treatment for equine and canine joint disorders, offering effective inflammation control without drugs. Its use is especially favored in performance animals, racehorses, and sport dogs, providing pain relief, joint preservation, and enhanced recovery. buy irap injection for horses